The Diabetes Prevention Program: Replicating/Translating the Results
نویسندگان
چکیده
منابع مشابه
The cost-effectiveness of diabetes prevention: results from the Diabetes Prevention Program and the Diabetes Prevention Program Outcomes Study
BACKGROUND The Diabetes Prevention Program (DPP) was a randomized, controlled clinical trial. It demonstrated that among high-risk individuals with impaired glucose tolerance, diabetes incidence was reduced by 58 % with lifestyle intervention and 31 % with metformin compared to placebo. During the Diabetes Prevention Program Outcomes Study (DPPOS), all DPP participants were unmasked to their tr...
متن کاملGWAS results in the Diabetes Prevention Program EXTENSION OF TYPE 2 DIABETES GENOME-WIDE ASSOCIATION SCAN RESULTS IN THE DIABETES PREVENTION PROGRAM
1 Center for Human Genetic Research and 2 Diabetes Center, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts; 3 Department of Medicine, Harvard Medical School, Boston, Massachusetts; 4 Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts; 5 The Biostatistics Center, George Washington University, Rockville, Maryland;...
متن کاملThe Diabetes Prevention Care Program
Diabetes is a common and costly chronic health condition. Afflicting slightly more than 3% of Kaiser Permanente North Carolina (KPNC) members, this condition is responsible for increased rates of myocardial infarction, stroke, kidney disease, and limb amputation. The medical management of these patients leads to dramatically higher health care costs than for nondiabetic patients. In 1995, the e...
متن کاملExtension of Type 2 Diabetes Genome-Wide Association Scan Results in the Diabetes Prevention Program
OBJECTIVE Genome-wide association scans (GWASs) have identified novel diabetes-associated genes. We evaluated how these variants impact diabetes incidence, quantitative glycemic traits, and response to preventive interventions in 3,548 subjects at high risk of type 2 diabetes enrolled in the Diabetes Prevention Program (DPP), which examined the effects of lifestyle intervention, metformin, and ...
متن کاملStatin use and risk of developing diabetes: results from the Diabetes Prevention Program
OBJECTIVE Several clinical trials of cardiovascular disease prevention with statins have reported increased risk of type 2 diabetes (T2DM) with statin therapy. However, participants in these studies were at relatively low risk for diabetes. Further, diabetes was often based on self-report and was not the primary outcome. It is unknown whether statins similarly modify diabetes risk in higher ris...
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ژورنال
عنوان ژورنال: The Diabetes Educator
سال: 2009
ISSN: 0145-7217,1554-6063
DOI: 10.1177/01457217090350020301